NEUROFIBROMATOSIS IN PREGNANCY: A CASE REPORT

Neurofibromatosis in Pregnancy

Abstract

This case report presents a 25-year-old primigravida diagnosed with Neurofibromatosis Type 1 (NF1) at 38 weeks gestation. The patient, with a familial history of similar skin lesions, complained of 24-hour liquor drainage and 8-hour labour pains. Clinical examination revealed café au lait spots and increasing cutaneous and subcutaneous NF lesions throughout pregnancy. While cardiovascular and neurosurgical assessments were unremarkable, an obstetric examination indicated a breech presentation. Routine screening identified the patient as hepatitis B-positive. Laboratory investigations showed no major abnormalities except for a breech presentation. A caesarean delivery was performed, resulting in the birth of a live male neonate with genus varus and bilateral talipes equinovarus. The newborn received timely hepatitis B immunoglobulin. The patient was discharged on the fourth postpartum day. This case underscores the challenges and considerations of managing pregnancies complicated by NF1, emphasising the need for multidisciplinary care.